Check out this vintage Anacin ad, which promises "a special 'mood-lifter' or energizer" to go with your aspirin. That depression-reducing agent? Caffeine. Why pay a therapist when the two things you use to cure hangovers will also cure the depression that caused you to drink in the first place? (Click the picture to read the ad in all its glory). [Modern Mechanix]
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So, basically Anacin was Midol.