When a woman is called "moody" or "emotional," it's often a thinly veiled way of saying "weak." The truth is that women are 1.5 to 3 times more likely to suffer from major depressive disorder than men. "There is growing evidence that estrogens have powerful effects beyond their role in reproduction — that they play a critical role in mood disorders in women," says Kathy Hegadoren, the Canada Research Chair in Stress Disorders in Women at the University of Alberta. "This opens new avenues for research into the underlying biological mechanisms and treatment of depression." The interesting part is that the rates of mood and anxiety disorders for little boys and little girls are fairly similar. But then something happens to girls that doesn't happen to boys.
It's only after females begin menstrual function that a gender differential in mood disorders manifests itself. This, coupled with the observation that women appear to be especially vulnerable to mood disturbances during times of hormonal flux, certainly lends support to the claim that a relationship exists between sex hormones and mood.
The real question is this: Does it make you feel better to know that being "moody" isn't just a "silly girl thing" but has actual scientific causes? Or does it make you feel worse, to know that men pretty much have a free pass to call women "hormonal" or "hysterical" or, sigh, "moody" ?
What Is The Link Between Women's Hormones And Mood Disorders? [Science Daily]